幼童患有阻塞型睡眠呼吸中止症候群者當心跳低時其HRV較正常者高,但心跳中或高時則剛好相反

Heart rate variability in children with obstructive sleep apnea.

ALJADEFF G, GOZAL D, SCHECHTMAN VL, BURRELL B, HARPER RM, WARD SL.

Sleep 1997;20(2):151-7.
Division of Pediatric Pulmonology, Childrens Hospital Los Angeles, University of Southern California School of Medicine, USA

Abstract:
Adults with obstructive sleep apnea syndrome (OSAS) display substantial heart rate changes associated with obstructive events, and recent reports suggest similar heart rate changes in children with OSAS. These rate changes could assist screening of young patients for OSAS. Six-hour polysomnographic recordings were obtained from seven children with OSAS (mean age: 4.5 years; apnea index: 19.5 +/- 5.1) and from seven primary snorers without OSAS who served as controls (mean age: 4.7; apnea index: 0). Scatterplots of each cardiac R-R interval against the preceding interval (Poincare plots) were used to assess beat-to-beat cardiac variability at different heart rates. Beat-to-beat variation at slow rates was significantly increased in children with OSAS relative to controls, while variation at fast and intermediate heart rates was significantly reduced in these children. We conclude that OSAS alters beat-to-beat variation in characteristic fashions in children, that the variability changes occur at all heart rates but are most significant at slow heart rates, and that these heart rate patterns could assist in screening of suspected cases of OSAS.